An ensemble method of the machine learning to prognosticate the gastric cancer

Hirad Baradaran Rezaei (), Alireza Amjadian (), Mohammad Vahid Sebt (), Reza Askari () and Abolfazl Gharaei ()
Additional contact information
Hirad Baradaran Rezaei: Amirkabir University of Technology
Alireza Amjadian: Kharazmi University
Mohammad Vahid Sebt: Kharazmi University
Reza Askari: Kharazmi University
Abolfazl Gharaei: Kharazmi University

Annals of Operations Research, 2023, vol. 328, issue 1, No 6, 192 pages

Abstract: Abstract Gastric Cancer is the most common malignancy of the digestive tract, which is the third leading cause of cancer-related mortality worldwide. The early prognosis methods, especially Machine Learning (ML)-based approaches are one of the main strategies against GC, which have become a necessity to identify and prognosticate the factors that affect the GC. They enable the specialists to accelerate the subsequent clinical management of patients, who suffer from the GC. This paper aims at creating an Ensemble Method inspired from ML to predict the most significant factors of the GC occurrence. The main objective of this research is to predict the probabilities of the GC occurrence and its associated deaths. To achieve this goal, the created EM benefits from some ML-based methods, including Least Absolute Shrinkage and Selection Operator (LASSO)/Ridge Regression, Elastic Net, Logistic Regression (LR), Random Forest (RF), Gradient Boosting Decision Trees (GBDTs), and Deep Neural Network (DNN). The purpose of the provided EM is to lessen the prediction errors for the large number of the patients’ features. The main novelties of this research include: (i) A sequential EM created by a Stacking method to predict the probability of the GC and associated deaths; (ii) Benefiting from the significance level to make an accurate prediction; (iii) Employing two Chi-square tests to select the influent features; (iv) Tuning the parameters of the applied ML models to avoid over-fitting and intensifying the errors; (v) Applying different kinds of the regression methods to treat hyper-dimension cases; (vi) A new model for weighting the applied ML models. The outcomes of the implementation of the created EM in seven pioneer hospitals in the field of GC show that the designed EM generates more precise predictions with an accuracy of 97.9% and 76.3% to predict the GC and its associated deaths, respectively. Moreover, the obtained results from the Area Under Curve (AUC) validates and confirms the capability of the created EM to predict the probability of the GC and its related deaths with an accuracy of 98% and 90% to predict the GC and its associated deaths, respectively.

Keywords: Gastric cancer; Ensemble learning; Machine learning; Classification; Mutual information; Stacking (search for similar items in EconPapers)
Date: 2023
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
http://link.springer.com/10.1007/s10479-022-04964-1 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:spr:annopr:v:328:y:2023:i:1:d:10.1007_s10479-022-04964-1

Ordering information: This journal article can be ordered from
http://www.springer.com/journal/10479

DOI: 10.1007/s10479-022-04964-1

Access Statistics for this article

Annals of Operations Research is currently edited by Endre Boros

More articles in Annals of Operations Research from Springer
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().