Antibiotic-Induced Liver Injury in Paediatric Outpatients: A Case-Control Study in Primary Care Databases

Carmen Ferrajolo (), Katia M. C. Verhamme, Gianluca Trifirò, Geert W. ‘t Jong, Gino Picelli, Carlo Giaquinto, Giampiero Mazzaglia, Bruno H. Stricker, Francesco Rossi, Annalisa Capuano and Miriam C. J. M. Sturkenboom
Additional contact information
Carmen Ferrajolo: University of Campania
Katia M. C. Verhamme: Erasmus University Medical Centre
Gianluca Trifirò: Erasmus University Medical Centre
Geert W. ‘t Jong: Erasmus University Medical Centre
Gino Picelli: Pedianet-Società Servizi Telematici SRL
Carlo Giaquinto: Pedianet-Società Servizi Telematici SRL
Giampiero Mazzaglia: Italian College of General Practitioners
Bruno H. Stricker: Erasmus University Medical Centre
Francesco Rossi: University of Campania
Annalisa Capuano: University of Campania
Miriam C. J. M. Sturkenboom: Erasmus University Medical Centre

Drug Safety, 2017, vol. 40, issue 4, No 4, 305-315

Abstract: Abstract Introduction Antibiotics are the most commonly prescribed drug class in children. Real-world data mining on the paediatric population showed potential associations between antibiotic use and acute liver injury. Objective We assessed risk estimates of liver injury associated with antibiotic use in children and adolescent outpatients. Methods A large, multi-database, population-based, case-control study was performed in people

Keywords: Liver Injury; Ceftriaxone; Clarithromycin; Index Date; Cefaclor (search for similar items in EconPapers)
Date: 2017
References: View complete reference list from CitEc
Citations: View citations in EconPapers (2)

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DOI: 10.1007/s40264-016-0493-y

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