Determinants of utilisation differences for cancer medicines in Belgium, Scotland and Sweden

Alessandra Ferrario ()
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Alessandra Ferrario: London School of Economics and Political Science

The European Journal of Health Economics, 2017, vol. 18, issue 9, No 4, 1095-1105

Abstract: Abstract Background Little comparative evidence is available on utilisation of cancer medicines in different countries and its determinants. The aim of this study was to develop a statistical model to test the correlation between utilisation and possible determinants in selected European countries. Methods A sample of 31 medicines for cancer treatment that obtained EU-wide marketing authorisation between 2000 and 2012 was selected. Annual data on medicines’ utilisation covering the in- and out-patient public sectors were obtained from national authorities between 2008 and 2013. Possible determinants of utilisation were extracted from HTA reports and complemented by contacts with key informants. A longitudinal mixed effect model was fitted to test possible determinants of medicines utilisation in Belgium, Scotland and Sweden. Results In the all-country model, the number of indications reimbursed positively correlated with increased consumption of medicines [one indication 2.6, 95% CI (1.8–3.6); two indications 2.4, 95% CI (1.4–4.3); three indications 4.9, 95% CI (2.2–10.9); all P

Keywords: Medicines utilisation; Multilevel mixed-effects data models; Oncology; Managed entry agreements; Pharmaceutical policy (search for similar items in EconPapers)
JEL-codes: I10 I14 (search for similar items in EconPapers)
Date: 2017
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DOI: 10.1007/s10198-016-0855-5

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