Resonant activation in a stochastic Hodgkin-Huxley model: Interplay between noise and suprathreshold driving effects

E. V. Pankratova (), A. V. Polovinkin and E. Mosekilde

The European Physical Journal B: Condensed Matter and Complex Systems, 2005, vol. 45, issue 3, 391-397

Abstract: The paper considers an excitable Hodgkin-Huxley system subjected to a strong periodic forcing in the presence of random noise. The influence of the forcing frequency on the response of the system is examined in the realm of suprathreshold amplitudes. Our results confirm that the presence of noise has a detrimental effect on the neuronal response. Fluctuations can induce significant delays in the detection of an external signal. We demonstrate, however, that this negative influence may be minimized by a resonant activation effect: Both the mean escape time and its standard deviation exhibit a minimum as functions of the forcing frequency. The destructive influence of noise on the interspike interval can also be reduced. With driving signals in a certain frequency range, the system can show stable periodic spiking even for relatively large noise intensities. Outside this frequency range, noise of similar intensity destroys the regularity of the spike trains by suppressing the generation of some of the spikes. Copyright EDP Sciences/Società Italiana di Fisica/Springer-Verlag 2005

Date: 2005
References: View complete reference list from CitEc
Citations: View citations in EconPapers (7)

Downloads: (external link)
http://hdl.handle.net/10.1140/epjb/e2005-00187-2 (text/html)
Access to full text is restricted to subscribers.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:spr:eurphb:v:45:y:2005:i:3:p:391-397

Ordering information: This journal article can be ordered from
http://www.springer.com/economics/journal/10051

DOI: 10.1140/epjb/e2005-00187-2

Access Statistics for this article

The European Physical Journal B: Condensed Matter and Complex Systems is currently edited by P. Hänggi and Angel Rubio

More articles in The European Physical Journal B: Condensed Matter and Complex Systems from Springer, EDP Sciences
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().