Life course socioeconomic adversities and 10-year risk of cardiovascular disease: cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health

Dayse Rodrigues Sousa Andrade, Lidyane V. Camelo, Rodrigo Citton P. Reis, Itamar S. Santos, Antonio Luiz Ribeiro, Luana Giatti and Sandhi Maria Barreto ()
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Dayse Rodrigues Sousa Andrade: Universidade Federal de Minas Gerais
Lidyane V. Camelo: Universidade Federal de Minas Gerais
Rodrigo Citton P. Reis: Universidade Federal de Minas Gerais
Itamar S. Santos: Universidade de São Paulo
Antonio Luiz Ribeiro: Universidade Federal de Minas Gerais
Luana Giatti: Universidade Federal de Minas Gerais
Sandhi Maria Barreto: Universidade Federal de Minas Gerais

International Journal of Public Health, 2017, vol. 62, issue 2, No 13, 283-292

Abstract: Abstract Objectives To investigate whether life course exposure to adverse socioeconomic positions (SEP) as well as maintaining a low SEP or decreasing the SEP intra- and intergeneration was associated with an increased 10-year cardiovascular disease (CVD) risk predicted by the Framingham Risk Score. Methods This is a cross-sectional analysis of baseline data (2008–2010) of 13,544 active workers from ELSA-Brasil cohort. Maternal education, leg length, social class of first occupation and education were used to evaluate childhood, youth and adulthood SEP. Results After considering adulthood SEP, exposure to early-life low SEP remained associated with an increased 10-year CVD risk. The 10-year CVD risk also rose as the number of exposures to low SEP throughout life increased. Compared to individuals in high-stable intragenerational trajectory, those in upward, downward, or stable low trajectory presented higher 10-year CVD risk. Increasing individuals’ SEP over generation showed no increased risk of 10-year CVD risk compared to individuals in high-stable trajectory. Conclusions Childhood may be a critical period for exposures to social adversities. Life course low SEP may also affect the 10-year CVD risk via accumulation of risk and social mobility.

Keywords: Socioeconomic position; Life course; Social mobility; Cardiovascular disease; Framingham Risk Score (search for similar items in EconPapers)
Date: 2017
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DOI: 10.1007/s00038-016-0928-3

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