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Marginalized mixture models for count data from multiple source populations

Habtamu K. Benecha (), Brian Neelon (), Kimon Divaris () and John S. Preisser ()
Additional contact information
Habtamu K. Benecha: USDA
Brian Neelon: Medical University of South Carolina
Kimon Divaris: University of North Carolina
John S. Preisser: University of North Carolina

Journal of Statistical Distributions and Applications, 2017, vol. 4, issue 1, 1-17

Abstract: Abstract Mixture distributions provide flexibility in modeling data collected from populations having unexplained heterogeneity. While interpretations of regression parameters from traditional finite mixture models are specific to unobserved subpopulations or latent classes, investigators are often interested in making inferences about the marginal mean of a count variable in the overall population. Recently, marginal mean regression modeling procedures for zero-inflated count outcomes have been introduced within the framework of maximum likelihood estimation of zero-inflated Poisson and negative binomial regression models. In this article, we propose marginalized mixture regression models based on two-component mixtures of non-degenerate count data distributions that provide directly interpretable estimates of exposure effects on the overall population mean of a count outcome. The models are examined using simulations and applied to two datasets, one from a double-blind dental caries incidence trial, and the other from a horticultural experiment. The finite sample performance of the proposed models are compared with each other and with marginalized zero-inflated count models, as well as ordinary Poisson and negative binomial regression.

Keywords: Dental caries; Excess zeros; Marginal inference; Mixture model; Over-dispersion; Zero-inflation (search for similar items in EconPapers)
Date: 2017
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Citations: View citations in EconPapers (1)

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DOI: 10.1186/s40488-017-0057-4

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