A Head-to-Head Comparison of the EQ-5D-5L and AQoL-8D Multi-Attribute Utility Instruments in Patients Who Have Previously Undergone Bariatric Surgery

Julie Campbell, Andrew J. Palmer, Alison Venn, Melanie Sharman, Petr Otahal and Amanda Neil ()
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Andrew J. Palmer: University of Tasmania
Alison Venn: University of Tasmania
Melanie Sharman: University of Tasmania
Petr Otahal: University of Tasmania
Amanda Neil: University of Tasmania

The Patient: Patient-Centered Outcomes Research, 2016, vol. 9, issue 4, No 4, 322 pages

Abstract: Abstract Background Psychosocial health status is an important and dynamic outcome for bariatric/metabolic surgery patients, as acknowledged in recent international standardised outcomes reporting guidelines. Multi-attribute utility-instruments (MAUIs) capture and assess an individual’s health-related quality-of-life (HRQoL) within a single valuation, their utility. Neither MAUIs nor utilities were discussed in the guidelines. Many MAUIs (e.g. EQ-5D) target physical health. Not so the AQoL-8D. Objectives Our objective was to explore agreement between, and suitability of, the EQ-5D-5L and AQoL-8D for assessing health state utility, and to determine whether either MAUI could be preferentially recommended for metabolic/bariatric surgery patients. Methods Utilities for post-surgical private-sector patients (n = 33) were assessed using both instruments and summary statistics expressed as mean [standard deviation (SD)] and median [interquartile range (IQR)]. Interchangeability of the MAUIs was assessed with Bland–Altman analysis. Discriminatory attributes were investigated through floor/ceiling effects and dimension-to-dimension comparisons. Spearman’s rank measured associations between the instruments’ utility values and with the body mass index (BMI). Results Mean (SD) EQ-5D-5L utility value was 0.84 (0.15) and median 0.84 (IQR 0.75–1.00). Mean (SD) AQoL-8D utility value was 0.76 (0.17) and median 0.81 (IQR 0.63–0.88). Spearman’s rank was r = 0.68; (p

Date: 2016
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DOI: 10.1007/s40271-015-0157-5

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