Measuring Health Spillover Effects in Caregivers of Children with Autism Spectrum Disorder: A Comparison of the EQ-5D-3L and SF-6D

Clare C. Brown, J. Mick Tilford (), Nalin Payakachat, D. Keith Williams, Karen A. Kuhlthau, Jeffrey M. Pyne, Renske J. Hoefman and Werner Brouwer
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Clare C. Brown: University of Arkansas for Medical Sciences
J. Mick Tilford: University of Arkansas for Medical Sciences
Nalin Payakachat: University of Arkansas for Medical Sciences
D. Keith Williams: University of Arkansas for Medical Sciences
Karen A. Kuhlthau: Harvard Medical School
Jeffrey M. Pyne: Center for Mental Healthcare and Outcomes Research, Central Arkansas Veterans Healthcare System and Psychiatric Research Institute, University of Arkansas for Medical Sciences
Renske J. Hoefman: Erasmus University

PharmacoEconomics, 2019, vol. 37, issue 4, No 15, 609-620

Abstract: Abstract Background and Objective Healthcare interventions that improve the health of children with autism spectrum disorder (ASD) have the potential to affect the health of caregivers. This study compares the three-level EuroQoL-5 Dimension (EQ-5D-3L) and the Short Form-6 Dimension (SF-6D) in their ability to value such spillover effects in caregivers. Methods Clinical data collected from two Autism Treatment Network (ATN) sites was combined with survey data of caregivers of children diagnosed with ASD. Caregivers completed instruments by proxy describing child health and completed the EQ-5D-3L and SF-6D preference-weighted instruments to describe their own health. Results There was a strong correlation between the health utility scores of the two preference-weighted instruments (ρ = 0.6172, p

Date: 2019
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DOI: 10.1007/s40273-019-00789-2

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