Putting Stakeholder Engagement at the Center of Health Economic Modeling for Health Technology Assessment in the United States

Richard Z. Xie (), Erica deFur Malik, Mark T. Linthicum and Jennifer L. Bright
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Richard Z. Xie: Innovation and Value Initiative
Erica deFur Malik: Innovation and Value Initiative
Mark T. Linthicum: Innovation and Value Initiative
Jennifer L. Bright: Innovation and Value Initiative

PharmacoEconomics, 2021, vol. 39, issue 6, No 4, 638 pages

Abstract: Abstract While evidence generated from health economic (HE) models is being used more commonly in health technology assessment (HTA) in the US, it is not consistently adopted by different stakeholder groups or across therapeutic areas. We hypothesize that actively engaging with multiple stakeholder groups throughout the model development process may result in models more widely considered by decision makers. To test this hypothesis, the Innovation and Value Initiative has launched a modeling effort to build an open-source HE model focusing on the disease state ‘major depressive disorder’. A 20-member advisory group has been formed with representatives from patients, employers, clinicians, innovators, payers, and researchers to guide the model development process. While this effort is still in the early stages, the ongoing stakeholder engagement effort has yielded valuable insights that inform the model design. We have also identified several challenges to implementing this new approach. Our early findings suggest that the stakeholder engagement approach to HE model development has the potential to improve HTA in the US.

Date: 2021
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DOI: 10.1007/s40273-021-01036-3

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