 Finite element study of a tissue-engineered cartilage transplant in human tibiofemoral jointAli Vahdati and Diane Wagner Computer Methods in Biomechanics and Biomedical Engineering, 2012, vol. 15, issue 11, 1211-1221 Abstract: Most tissue-engineered cartilage constructs are more compliant than native articular cartilage (AC) and are poorly integrated to the surrounding tissue. To investigate the effect of an implanted tissue-engineered construct (TEC) with these inferior properties on the mechanical environment of both the engineered and adjacent native tissues, a finite element study was conducted. Biphasic swelling was used to model tibial cartilage and an implanted TEC with the material properties of either native tissue or a decreased elastic modulus and fixed charged density. Creep loading was applied with a rigid impermeable indenter that represented the femur. In comparison with an intact joint, compressive strains in the transplant, surface contact stress in the adjacent native AC and load partitioning between different phases of cartilage were affected by inferior properties of TEC. Results of this study may lead to a better understanding of the complex mechanical environment of an implanted TEC. Date: 2012 Downloads: (external link) Related works: Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text Persistent link: https://EconPapers.repec.org/RePEc:taf:gcmbxx:v:15:y:2012:i:11:p:1211-1221 Ordering information: This journal article can be ordered from DOI: 10.1080/10255842.2011.585974 Access Statistics for this article Computer Methods in Biomechanics and Biomedical Engineering is currently edited by Director of Biomaterials John Middleton More articles in Computer Methods in Biomechanics and Biomedical Engineering from Taylor & Francis Journals |
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