Monoclonal B-Cell Lymphocytosis- Compromise of the Immune System?

Mike A Celis and Wendy Nieto
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Mike A Celis: University of Santander, Faculty of Medical and Health Sciences, Masira Research Institute, Colombia
Wendy Nieto: International Hospital of Colombia, Department of Pathology, FCV Translational Biomedical Research Group, Colombia

Biomedical Journal of Scientific & Technical Research, 2023, vol. 48, issue 4, 40013-40014

Abstract: Monoclonal B-Cell Lymphocytosis (MBL) is part of the mature B-cell neoplasms despite actually being a pre-neoplastic condition [1], this entity, largely unstudied, affects more than 5-10% of older adults age 40 and the incidence increases with aging [2,3], MBL is widely associated as one of the main risk factors for developing Chronic Lymphocytic Leukemia (CLL)/Small Cell Lymphocytic Lymphoma (SLL), since studies Prospective cohort studies verified, in effect, that CLL is always preceded by MBL, therefore, the greater the number of clonal B cells, the greater the risk of developing this type of cancer [4]. However, it is not ruled out that MBL is implicated in the lymphomagenesis of other pathologies such as follicular lymphoma and mantle cell lymphoma [5].

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:48:y:2023:i:4:p:40013-40014

DOI: 10.26717/BJSTR.2023.48.007698

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