Cluster Analysis of RNA m6A Methylation Regulators Based on TCGA and GEO Database in Hepatocellular Carcinoma

Xiaoshi Zhang, Jianqiang Cai, Zhuo Yu and Xiaoyi Zhang
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Jianqiang Cai: National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China
Zhuo Yu: Beijing Hospital, China
Xiaoyi Zhang: Exchange, Development & Service Center for Science & Technology Talents, China

Biomedical Journal of Scientific & Technical Research, 2024, vol. 55, issue 3, 47045-47054

Abstract: As potential targets and candidate molecules for the treatment of cancer, m6 A RNA and its regulator genes have important application prospects in individualized therapy of Hepatocellular Carcinoma(HCC). Through TCGA and GEO data screening, we demonstrated the expression of different m6 A regulators within HCC related to genetic variation, biological pathways and patients’ prognosis. We use machine learning methods to cluster m6 A regulators and differential expressed genes, which may provide a theoretical basis for the establishment of a risk assessment model.

Keywords: Journals on Medical Drug and Therapeutics; Journals on Emergency Medicine; Physical Medicine and Rehabilitation; Journals on Infectious Diseases Addiction Science and Clinical Pathology; Open Access Clinical and Medical Journal; Journals on Biomedical Science; List of Open Access Medical Journal; Journals on Biomedical Engineering; Open Access Medical Journal; Biomedical Science Articles; Journal of Scientific and Technical Research (search for similar items in EconPapers)
Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:abf:journl:v:55:y:2024:i:3:p:47045-47054

DOI: 10.26717/BJSTR.2024.55.008713

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