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Which is the Preferred Measure of Heterogeneity in Meta-Analysis and Why? A Revisit

Mona Pathak, Sada Nand Dwivedi, Deo Svs, V Sreenivas and Bhaskar Thakur
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Mona Pathak: Department of Biostatistics, All India Institute of Medical Sciences, India
Sada Nand Dwivedi: Department of Biostatistics, All India Institute of Medical Sciences, India
Deo Svs: Department of Surgical Oncology, IRCH, All India Institute of Medical Sciences, India
V Sreenivas: Department of Biostatistics, All India Institute of Medical Sciences, India
Bhaskar Thakur: Department of Biostatistics, All India Institute of Medical Sciences, India

Biostatistics and Biometrics Open Access Journal, 2017, vol. 1, issue 1, 14-20

Abstract: Heterogeneity assessment is unavoidable under meta-analysis as it guides the path to choose appropriate synthesizing method. Its consideration further strengthens the drawn inferences. In the literature, there are various measures of heterogeneity, such as, Q statistic, H2 statistic, HM2 statistic, R2 statistic and I2 statistic. The present work mainly aimed to appraise all existing methods and find the preferred measure of heterogeneity in meta-analysis. Various heterogeneity measures were compared on the basis of theoretical criteria as well as their analytical results on the observed data from a systematic review of randomized controlled trials comparing neoadjuvant chemotherapy with adjuvant chemotherapy in the treatment of breast cancer patients.

Keywords: Biometrics Open Access Journal; Biostatistics and Biometrics; Biostatistics and Biometrics Open Access Journal; Open Access Journals; biometrics journal; biometrics articles; biometrics journal reference; biometrics journal impact factor; biometrics and biostatistics journal impact factor; journal of biometrics; open access juniper publishers; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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Persistent link: https://EconPapers.repec.org/RePEc:adp:jbboaj:v:1:y:2017:i:1:p:14-20

DOI: 10.19080/BBOAJ.2017.01.555555

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