Advances in Neutrophil Testing In Type 2 Diabetes Mellitus

Han Wei Hou, Hui Min Tay, Rinkoo Dalan and Bernhard O Boehm
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Han Wei Hou: Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
Hui Min Tay: Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
Rinkoo Dalan: Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
Bernhard O Boehm: Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

Current Research in Diabetes & Obesity Journal, 2017, vol. 1, issue 5, 92-96 2Volume: 1

Abstract: Patients with type 2 diabetes mellitus (T2DM) suffer from impaired glucose metabolism which results in low-grade inflammation and activation of the innate immune system. Neutrophils the key effector cells of the innate immune system and heavily implicated in the pathogenesis of T2DM, are promising cell-based inflammatory biomarkers for immune health profiling, provided that they can be rapidly purified and measured with sufficient precision. In this review, we highlight recent advances in neutrophil isolation and functional assay using microfluidics technologies and the potential of their functional phenotype as a novel biomarker of vascular risk in diabetes.

Keywords: juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jcrdoj:v:1:y:2017:i:5:p:92-96

DOI: 10.19080/CRDOJ.2017.01.55552

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