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The Mantle of Advanced Glycation End Products in Micro-and Macrovascular Complications of Type 2 Diabetes Mellitus

Attya Bhatti, Nida Ali Syed and Peter John
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Attya Bhatti: Department of Healthcare Biotechnology, National University of Sciences and Technology, Pakistan
Nida Ali Syed: Department of Healthcare Biotechnology, National University of Sciences and Technology, Pakistan
Peter John: Department of Healthcare Biotechnology, National University of Sciences and Technology, Pakistan

Current Research in Diabetes & Obesity Journal, 2017, vol. 2, issue 5, 83-87

Abstract: Type 2 Diabetes Mellitus is a multifactorial disease marked by chronic hyperglycemia and insulin resistance. Its associated vascular complications are a major contributor to mortality globally. These vascular complications are frequently implicated to be an offshoot of high levels of advanced glycation end products which are produced due to a persistent hyperglycemic and oxidative stress state. This review summarizes the role of advanced glycation end products in the pathogenesis of micro- and macrovascular complications of type 2 diabetes mellitus.

Keywords: juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jcrdoj:v:2:y:2017:i:5:p:83-87

DOI: 10.19080/CRDOJ.2017.02.555596

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