Effects of Metformin on Cytochromes CYP3Ð, CYP2С and CYP2Е1 Functioning at Metabolic Syndrome in Rats of Different Age

Bondarenko Larysa Borysivna, Shayakhmetova Ganna Mykhailivna, Voronina Alla Kostyantynivna and Kovalenko Valentyna Mykolaivna
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Bondarenko Larysa Borysivna: Department of Toxicology, Institute of Pharmacology & Toxicology National Academy of Medical Sciences of Ukraine, Ukraine
Shayakhmetova Ganna Mykhailivna: Department of Toxicology, Institute of Pharmacology & Toxicology National Academy of Medical Sciences of Ukraine, Ukraine
Voronina Alla Kostyantynivna: Department of Toxicology, Institute of Pharmacology & Toxicology National Academy of Medical Sciences of Ukraine, Ukraine
Kovalenko Valentyna Mykolaivna: Department of Toxicology, Institute of Pharmacology & Toxicology National Academy of Medical Sciences of Ukraine, Ukraine

Current Research in Diabetes & Obesity Journal, 2017, vol. 4, issue 4, 86-93

Abstract: The aim of our present study was to carry out a complex estimation of metabolic syndrome (MS) and metformin mediated changes in CYP3Р, CYP2С, CYP2Е1 mRNA expression and corresponding marker enzymes activities, as soon as liver antioxidant system and lipid peroxidation parameters of adult and pubertal rats.

Keywords: juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jcrdoj:v:4:y:2017:i:4:p:86-93

DOI: 10.19080/CRDOJ.2017.04.555645

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