Microneedles: A Potent Modern Tool in Enhancing Transdermal Drug Delivery

Ogundele Mi and Okafor Hk
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Ogundele Mi: Department of Biomedical Engineering, Binghamton University, USA
Okafor Hk: Department of Biochemistry, College of Medicine, University of Lagos, Nigeria

Current Trends in Biomedical Engineering & Biosciences, 2017, vol. 10, issue 1, 1-9

Abstract: The conventional drug delivery methods commonly used are oral administration and injection. However there a limitation posed against the penetration of these substances in therapeutic amounts via the corneum stratum. There has been an increasing emphasis on Transdermal drug delivery which provides a better prospect than the two conventional methods. Transdermal drug delivery provides quite a number of merits which include sustained release, prevention of gastric irritation, improvement in patience compliance as well as removal of pre-systemic first-pass effect. In recent times, microneedles are being proposed for use in enhancing Transdermal drug delivery as the use of microneedles increases skin permeability. This review is a qualitative attempt as discussing the microneedle as a potent modern tool in enhancing transdermal drug delivery. This starts with the explanation of the skin and microneedles. Then the mechanism of action of microneedles, the advantages and disadvantages of microneedles are also discussed. The review ends with the recent advances in the application of microneedles in transdermal drug delivery.

Keywords: juniper publishers group; juniper publishers Biomedical Engineering journals; Biomedical Engineering journals list; medical devices journals; peer reviewed Biomedical Engineering journals; open access Biomedical Engineering journals; Biomedical Engineering journals impact factor; Biomedical Engineering scientific journals; Biomedical Engineering articles; scholarly Biomedical Engineering journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jctbeb:v:10:y:2017:i:1:p:1-9

DOI: 10.19080/CTBEB.2017.10.555776

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