Factors that Determine Fatality of Rhesus Incompatibility

Seriki Sa
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Seriki Sa: Department of Human Physiology, Edo University, Nigeria

Global Journal of Reproductive Medicine, 2020, vol. 7, issue 4, 83-85 Volu2m: 7

Abstract: Erythroblastosisfetalis, otherwise described as Haemolytic Disease of the New-born (HDN)occurs when red blood cells (RBC) of fetus break quickly as a result of passage of immunoglobulin-G (IgG) molecules (an antibody produced by the mother) through the placenta into the fetal circulation causing serious reaction that tends to destroy the red cell of the fetus. The current study reviews the pathophysiology of the disease; specifically, it focuses on the factors that determine maternal response to sensitization and also the factors that determine the fatality of response in an exposure. Indeed, it examinesbetween volume of exposure, maternal immune sensitivity and recurrence of exposure, which determines response and fatality. The study observed that although maternal immune sensitivity determines how fast her body responds to sensitization (and not necessarily the volume), the fatality of response is dependent on volume and recurrence of exposure.

Keywords: Journal of Reproductive Medicine; Reproductive Medicine; journal of reproductive medicine; reproductive medicine articles; reproductive medicine articles impact factor; reproductive medicine research journals; reproductive journals list; open access; juniper publishers journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2020
References: View complete reference list from CitEc
Citations: View citations in EconPapers (1)

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Persistent link: https://EconPapers.repec.org/RePEc:adp:jgjorm:v:7:y:2020:i:4:p:83-85

DOI: 10.19080/GJORM.2020.07.555720

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