Phytochemical Characterization and Antioxidative Property of Ocimum canum Sims

R Kuralarasi and S Revathilakshmi
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R Kuralarasi: Research scholar, Ayya Nadar Janaki Akmal College, India
S Revathilakshmi: Department of Botany, Ayya Nadar Janaki Akmal College, India

Global Journal of Pharmacy & Pharmaceutical Sciences, 2019, vol. 7, issue 3, 77-82

Abstract: Medicinal plants are the richest bio-resource of drugs for traditional systems of medicine, modern medicine, nutraceuticals, food supplements, folk medicines, pharmaceutical intermediates and chemical entities for synthetic drugs. In the present study aimed to find out the phytochemicals present in the various solvent leaf extracts of Ocimum canum Sims and all the fractions of O. canum demonstrated H-donor activity. The highest DPPH radical scavenging activity was detected in chloroform fraction (IC50 0.145mg/ml), followed by ethyl acetate, pet-ether and residual fractions (IC50 0.164, 0.29 and 0.6mg/ml respectively). The residual fraction of O. canum showed the highest reducing ability (absorbance 0.620) than all the other fractions tested. The scavenging activity of the pet-ether fraction (IC50 0.141mg/ml) was higher than that of quercetin (0.308mg/ml). The residual, chloroform and ethyl acetate fractions also showed significant scavenging activities (IC50 of RF, CF and EAF were 0.125, 0.186 and 0.232mg/ml respectively) when compared to the standard.

Keywords: juniper publishers:Journal of Pharmacy; Global Journal of Pharmacy; Pharmaceutical Sciences; Pharmacy & Pharmaceutical Sciences; pharmaceutical sciences journals; omics online; open access; drug discovery; Clinical Trials; juniper publishers open access journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jgjpps:v:7:y:2019:i:3:p:77-82

DOI: 10.19080/GJPPS.2019.07.555712

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