Islet Cell Transplantation for Treating Type 1 Diabetes: The Bright Future of Drug Designing and Development

Mina T Kelleni
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Mina T Kelleni: Department of pharmacology, Minya University, Egypt

Novel Approaches in Drug Designing & Development, 2017, vol. 1, issue 3, 50-51

Abstract: The revolutionary process of islet transplantation for treating type 1 diabetes has been limited by the high level of graft failure. The process of islet isolation alone has been shown to negatively impact islet survival and function in vivo. In addition, insults mediated by the instant blood-mediated inflammatory reaction, hypoxia, ischemia and immune response significantly impact the islet allograft post transplantation [1,2]. Moreover, the immune response to alloantigens and recurrence of autoimmunity contribute to pancreatic islet transplant dysfunction [3].

Keywords: juniper publishers; drug designing pdf; drug designing articles; drug designing abstract; drug designing journal; modern approaches in drug designing journal; drug designing & intellectual properties international journal; peer reviewed open access journals; high impact journals; juniper publishers review (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jnapdd:v:1:y:2017:i:3:p:50-51

DOI: 10.19080/NAPDD.2017.01.555564

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