Stroke: Unifying Mechanism Involving Antioxidant Therapy, Reactive Oxygen Species, and Oxidative Stress

Peter Kovacic and Wil Weston
Additional contact information
Peter Kovacic: Department of Chemistry and Biochemistry, San Diego State University, San Diego, CA, USA
Wil Weston: Library and Information Access, San Diego State University, San Diego, CA, USA

Novel Approaches in Drug Designing & Development, 2018, vol. 4, issue 4, 88-94

Abstract: Reactive oxygen species (ROS) and oxidative stress (OS) play roles in stroke, as also in Alzheimer’s (AD), Parkinson’s (PD) disease and Schizophrenia (SCZ). Various sources, including oxidases, serve as generators of ROS-OS, such as mitochondria, NADPH, cytochromes P450, monoamines, ET metal complexes, G72 gene, and microglia. Many novel examples of antioxidants (AOs) exert a positive influence on the harmful effects, namely through a unifying mechanism based on ET-ROS-OS-AO. Drugs for treatment of stroke are discussed in relation to the unifying theme including phenolic and phenolic ethers.

Keywords: juniper publishers; drug designing pdf; drug designing articles; drug designing abstract; drug designing journal; modern approaches in drug designing journal; drug designing & intellectual properties international journal; peer reviewed open access journals; high impact journals; juniper publishers review (search for similar items in EconPapers)
Date: 2018
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://juniperpublishers.com/napdd/pdf/NAPDD.MS.ID.555641.pdf (application/pdf)
https://juniperpublishers.com/napdd/NAPDD.MS.ID.555641.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:adp:jnapdd:v:4:y:2018:i:4:p:88-94

DOI: 10.19080/NAPDD.2018.04.555641

Access Statistics for this article

Novel Approaches in Drug Designing & Development is currently edited by Sophia Mathis

More articles in Novel Approaches in Drug Designing & Development from Juniper Publishers Inc.
Bibliographic data for series maintained by Robert Thomas ().