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Prognostic Value of Red Cell Distribution Width in Acute Coronary Syndrome

Gerald Chi, Husnain Shaukat, Mehrian Jafarizade, Farima Kahe, Arzu Kalayci, Asrar Ahmad and Qasim Zulfiqar Malik
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Arzu Kalayci: Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, United States
Asrar Ahmad: Department of Medicine, Abington Memorial Hospital, United States
Qasim Zulfiqar Malik: Department of Medicine, Wright center for Graduate Medical Education, United States

Open Access Blood Research & Transfusion Journal, 2018, vol. 1, issue 4, 86-92

Abstract: Anisocytosis denotes the presence of unequal sizes of erythrocytes in the circulation and may signify the development of nutritional deficiency anemias, sickle cell anemia, hemolytic anemia, myelodysplastic syndrome, and other hematological disorders. Red cell distribution width (RDW), a quantitative measure of the magnitude of anisocytosis, is routinely reported as a part of complete blood count by automated instruments in hematology laboratories. An elevated RDW is commonly used in the differential diagnoses of nutritional deficiency anemias and thalassemias. Rapidly accruing evidence indicates that RDW may offer prognostic information regarding the clinical outcomes in various cardiovascular scenarios. This article aims to review the current knowledge concerning the predictive value of RDW in patients with acute coronary syndrome. Elevated RDW is a strong predictor for mortality and major adverse cardiac events among patients admitted with acute myocardial infarction. When incorporated into conventional risk assessment models, RDW also enhances the performance in predicting cardiovascular outcome. In light of its wide availability, low cost and common use, future research should consider RDW measurement in the risk stratification schemes for patients with coronary artery disease.

Keywords: Open Access Blood Research Journal; Open Access Blood Research & Transfusion Journal; juniper publishers; Open Access; Blood Research & Transfusion Journal; blood research impact factor; blood research topics; blood research paper; blood research & transfusion journa (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:joabtj:v:1:y:2018:i:4:p:86-92

DOI: 10.19080/OABTJ.2018.01.555570

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