The New Concepts for Leukemia Probably Especially in Chronic Myeloid Leukemia (CML) And Atypical CML (aCML)

Ahmad Reza Rahnemoon
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Ahmad Reza Rahnemoon: Department of Hematology, Iran University of Medical sciences, Iran

Open Access Blood Research & Transfusion Journal, 2018, vol. 2, issue 2, 41-47

Abstract: While leukemia has been recognized as a genomic disease, we must attention in epigenetic mechanisms in these patients. Thus, the active epigenetic marks particularly in histone protein modification and in other biological phenomena can be important in injury of any progenitor or precursor cell particularly hematopoietic stem cell (HSC) at BM microenvironment. Totally, every oncogenic event with epigenetic modifier or any cancer event can be deregulated the cells of BM niche. Here, I try to submit the role of HSC and how subverted in these diseases..

Keywords: Open Access Blood Research Journal; Open Access Blood Research & Transfusion Journal; juniper publishers; Open Access; Blood Research & Transfusion Journal; blood research impact factor; blood research topics; blood research paper; blood research & transfusion journa (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:joabtj:v:2:y:2018:i:2:p:41-47

DOI: 10.19080/OABTJ.2018.02.555585

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