Synthesis, Characterization, Thermodynamic and Biological Activity Studies for New Complexes of Some Transition Metals and Zinc With Schiff’s Bases [2,5di (1-Thi-Ophen-2-yl-Ethylidene)-Hydrazine) 1, 3, 4-Thiadiazole]

Cesar A C Sequeira
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Cesar A C Sequeira: Center of Physics and Engineering of Advanced Materials, Instituto Superior Técnico, University of Lisbon, Portugal

Organic & Medicinal Chemistry International Journal, 2018, vol. 5, issue 2, 60-71

Abstract: Because of their magnetic and superparamagnetic properties, iron oxide nanoparticles (IONPs) have many potential applications for medical use. The synthesis of these nanoparticles (NPs) has been the basis of many studies, each proposing different synthesis methods yielding nanostructures of different properties. In this review the synthesis of biologically compatible IONPs by electrochemical deposition is described, thus exploring their potential use in biomedical applications. The chemical, physical and magnetic properties of these nanostructures are examined to determine their possible application in magnetic resonance imaging (MRI) contrast enhancement and thermal activation therapy. NPs characterization and demonstration of their potential uses pave the way to the development of smart magnetic IONPs for targeted diagnostics and therapeutics of human diseases, including cancer and Alzheimer’s disease.

Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:5:y:2018:i:2:p:60-71

DOI: 10.19080/OMCIJ.2018.05.555660

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