Role of Chirality in Drugs

Reshma Jayakumar, Ragavi Vadivel and Nallamuthu Ananthi
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Reshma Jayakumar: PSGR Krishnammal College for Women, Indias
Nallamuthu Ananthi: Department of Chemistry, Karunya Institute of Technology and Sciences, India

Organic & Medicinal Chemistry International Journal, 2018, vol. 5, issue 3, 71-77

Abstract: About more than half of the drugs currently in use are chiral compounds. Although few drugs were used as racemates, most of the drugs are founds as single enantiomer. With the same chemical structure, most of the enantiomers of chiral drugs exhibit marked differences in biological activities such as pharmacology, toxicology, pharmacokinetics, metabolism etc. In this review we comprised some of the notable chiral drugs, their mechanism of action and their structure activity relationship.

Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:5:y:2018:i:3:p:71-77

DOI: 10.19080/OMCIJ.2018.05.555661

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