Variability of Clinical and Paraclinical Manifestations in Antiphospholipid Antibody Syndrome - Two Case Reports and Literature Review

Elena Laura Iliescu, Letitia Toma, Simona Ioanitescu, Mihai Dodot, Teodora Isac, Mihaela Grumeza, Adriana Mercan-Stanciu and Vlad Herlea
Additional contact information
Adriana Mercan-Stanciu: Department of Internal Medicine II, Fundeni Clinical Institute, Romania
Vlad Herlea: Department of Pathology, Fundeni Clinical Institute, Romania

Orthopedics and Rheumatology Open Access Journals, 2018, vol. 13, issue 1, 22-29

Abstract: Antiphospholipid antibody syndrome is a well- known, although rare, autoimmune condition characterized by thromboembolic events and/ or pregnancy morbidity, in the presence of antiphospholipid antibodies. We present the cases of two women (aged 59 and 37 years old), both diagnosed with this disease, but having different forms of manifestation; the first one consists of recurrent episodes of pulmonary embolies and renal impairment, with relatively late onset, while the second case describes early history of pregnancy morbidity in a young patient that also presents kidney function alterations; both patients have suggestive serology. A kidney biopsy was performed in both cases. The particularity of antiphospholipid syndrome as a pathological entity consists in its clinical variability and heterogenicity, therefore, whenever there are signs of thrombosis or pregnancy complications, this condition must be suspected and further investigated.

Keywords: journal of orthopaedics; orthopaedics journals impact factor; orthopaedics articles impact factor; scholarly publishing orthopedics journals; juniper publishers opena ccess orthopedics journal; Rheumatology; rheumatology journals impact factor 2018; rheumatology journals impact factor; rheumatology open access journals; juniper publishers review (search for similar items in EconPapers)
Date: 2018
References: Add references at CitEc
Citations:

Downloads: (external link)
https://juniperpublishers.com/oroaj/pdf/OROAJ.MS.ID.55585.pdf (application/pdf)
https://juniperpublishers.com/oroaj/OROAJ.MS.ID.55585.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:adp:joroaj:v:13:y:2018:i:1:p:22-29

DOI: 10.19080/OROAJ.2018.13.55585

Access Statistics for this article

Orthopedics and Rheumatology Open Access Journals is currently edited by Sophia Mathis

More articles in Orthopedics and Rheumatology Open Access Journals from Juniper Publishers Inc.
Bibliographic data for series maintained by Robert Thomas ().