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An Unusual Presentation of CNS Histoplasmosis Mimicking Metastatic Cancer

Prashanth Moku, Shady Piedra Abusharar, Fahad M Khalid, Rashmi Banjade and Hyma Polimera
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Hyma Polimera: Penn State College of Medicine, USA

Juniper Online Journal of Case Studies, 2019, vol. 10, issue 4, 69-71

Abstract: Histoplasma Capsulatum is a thermally dimorphic fungus that is known to cause histoplasmosis. Inhalation of Histoplasma microconidia into alveolar spaces transforms them into yeasts. Most histoplasma infections are mild or asymptomatic in immunocompetent individuals. However, affected individuals often present with manifestations of an inflammatory response to this infection. Patients often present with bone marrow suppression (pancytopenia) and elevated liver enzymes [1]. Clinical evaluation reveals a flu-like illness with findings of fever, headache, myalgia, dyspnea, chest pain and infection localized to the lungs [2]. Additional manifestations can include involvement of adrenal glands, central nervous system, and skin [3]. Herein, we present a case of disseminated histoplasmosis complicated by CNS and adrenal gland involvement.

Keywords: Online Journal of Case Studies; Journal of Case Studies; juniper publishers; open access journals; case studies examples; case studies with solutions; case studies pdf; juniper publishers reivew (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:adp:ojojcs:v:10:y:2019:i:4:p:69-71

DOI: 10.19080/JOJCS.2019.10.555791

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