The role of vitamin E In reducing the side effects of Gabapentin on some physiological parameters related to the heart in male albino rats

Sarah A. Hassoun () and Hanaa E. Mahood ()

Edelweiss Applied Science and Technology, 2024, vol. 8, issue 6, 1287-1290

Abstract: The study was designed to evaluate the role of vitamin E in reducing the side effects of gabapentin on some physiological parameters related to the heart in male albino rats,(30) males were used, who were divided into three equal groups : The control group was given physiological saline solution in concentration( 0.9% ), the treatment group T1 was given gabapentin at a concentration of (100mg / Kg) of body weight, treatment group (T2) was given gabapentin at a concentration of (100mg / Kg) of body weight and vitamin E at a concentration of 80 mg/kg of body weight, the results revealed that gabapentin causes significant increase in some parameters related to the heart,Vitamin E helped reduce them.

Keywords: CPK; LDH; Myo; Gabapentin; Vitamin E; Tropo. (search for similar items in EconPapers)
Date: 2024
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