Photodynamic Therapy Using Endoscopy Capsule Robot

Sherif Hamdy ElGohary, Yomna Sabah Mohamed, Mennatallah Hany Elkhodary, Omnya Ahmed and Mennatallah Hesham
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Sherif Hamdy ElGohary: Department of Biomedical Engineering and Systems, Faculty of Engineering, Cairo University, 12613, Cairo, Egypt Healthcare Engineering and Management Department, Cairo University Faculty of Engineering, Cairo, Egypt
Yomna Sabah Mohamed: Healthcare Engineering and Management Department, Cairo University Faculty of Engineering, Cairo, Egypt
Mennatallah Hany Elkhodary: Healthcare Engineering and Management Department, Cairo University Faculty of Engineering, Cairo, Egypt
Omnya Ahmed: Healthcare Engineering and Management Department, Cairo University Faculty of Engineering, Cairo, Egypt
Mennatallah Hesham: Healthcare Engineering and Management Department, Cairo University Faculty of Engineering, Cairo, Egypt

Academic Journal of Life Sciences, 2020, vol. 6, issue 7, 93-100

Abstract: Among the photosensitizers used in Photodynamic therapy (PDT) technique for cancer treatment, it is found out that the Methylene blue and glycoconjugates chlorine are the best ones for this purpose. In this paper, it is suggested to use Active Capsule Wireless Endoscopy Robot instead of the traditional endoscope. The capsule has many valuable features. It uses LEDs as a source of light in the PDT to kill the colon cancer cells. So, the doctor can make use of the advantage of applying the LED light locally at the tumor which was previously injected by the photosensitizers, the light activates these photosensitizers and a photochemical reaction starts that makes the colon cancer cells die. The light with effective wavelength and power density, energy level and controlled LED light intensity will be applied. Active locomotion capsule endoscopy with an electromagnetic actuation system that can achieve a 3-D locomotion and guidance within the digestive system. The paper also discussed how to manage the required power in the capsule for all parts, LEDs, camera, transceiver, and locomotion.

Keywords: Photodynamic therapy; Photosensitizers; Wireless capsule; Endoscopy; Colon cancer; Photochemical reaction. (search for similar items in EconPapers)
Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:arp:ajlsar:2020:p:93-100

DOI: 10.32861/ajls.67.93.100

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