Assessment of the Risk of Myocardial Infarction among Undergraduate Students in a Nigerian Tertiary Institution

Ugwu C. E., Nwankwo S. E., Meludu S. C. and Nnodim J. K.
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Ugwu C. E.: Department of Human Biochemistry, Faculty of Basic Medical Sciences Nnamdi Azikiwe University Nnewi campus
Nwankwo S. E.: Department of Medical Laboratory Sciences, Faculty of Health Sciences and Technology Nnamdi Azikiwe University Nnewi campus
Meludu S. C.: Department of Human Biochemistry, Faculty of Basic Medical Sciences Nnamdi Azikiwe University Nnewi campus
Nnodim J. K.: Department of Medical Laboratory Sciences, Faculty of Health Sciences, Imo State University Owerri, Nigeria

International Journal of Healthcare and Medical Sciences, 2016, vol. 2, issue 11, 60-65

Abstract: Background; Myocardial Infarction (MI) is a term which is used for defining the necrosis in the heart muscle due to the lack of the oxygen need of myocardium which cannot be supplied by the coronaries. Aim: This study was carried out to determine the effects of some lifestyle and anthropometric parameters on some cardiac enzymes. Methods: A total of 146 students of sex, age bracket, (16 - 30) were recruited for this study. Enzymatic methods were used in the determination of AST, ALT, CKMB activities. Anthropometric measurements of the participants were taken. The result showed that there was significant increase in systolic blood pressure (SBP), weight and height (p 0.05) in the serum ALT, AST, and CKMB activities. However, there was significant difference in ALT and AST activities (P 0.05). Statistically the percentage of the participants that had their serum ALT activity above the reference range were 16.6%, those within the reference range were 83.4%,. In serum AST activity, the percentage above the reference range were 19.9%, those within the reference range were 80.1%. Meanwhile, in serum CK-MB activity, those above the reference range were 25.2% while those within the reference range were 74.8%. Conclusion: This could be probably indicate that the leakage of AST and ALT activities may be of hepatic origin. . The non-significant increase in CKMB which is a specific marker of myocardial injury, could suggest that the subjects were not at risk of developing of myocardial infarction as regards their age.

Keywords: Myocardial infarction; Undergraduate students; Nigerian tertiary Institution. (search for similar items in EconPapers)
Date: 2016
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