Amelioration of Gentamicin Induced Dyslipidemia in Guinea Pigs by Curcumin and Rosemary

Munira Ammar Algridi and Azab Elsayed Azab
Additional contact information
Munira Ammar Algridi: Department of Zoology, Faculty of Science, Alejelat, Zawia University, Libya
Azab Elsayed Azab: Department of Zoology, Faculty of Science, Alejelat, Zawia University, Libya

Scientific Review, 2017, vol. 3, issue 2, 6-16

Abstract: The present study aimed to evaluate the effectiveness of curcumin, and Rosemary as a natural source of antioxidants to minimize the harmful effects of gentamicin induced dyslipidemia in Guinea pigs. Guinea pigs were divided into five groups. The first group (control) was injected intraperitoneal with saline. The 2nd group was injected intraperitoneal with gentamicin at a dose of 100 mg/kg body weight /day. The 3th , 4th , and 5th groups were injected intraperitoneal with gentamicin (100 mg/kg b. wt /day) concurrently with curcumin, rosemary, and curcumin with rosemary at the doses of 200 mg, 220 mg, and 200 mg with 220 mg /kg body weight /day respectively orally by gavage for 10 days. Blood samples were obtained for assessment of serum cholesterol, triglycerides, high density lipids, low density lipids, and very low density lipids concentrations. Gentamicin treatment induced dyslipidemia. Guinea pigs that injected intraperitonally with gentamicin at a dose of 100 mg/kg body weight daily for 10 days had significantly (p

Keywords: Dyslipidemia; Curcumin; Gentamicin; Rosemary; Hypolipidemic effect; Guinea Pigs. (search for similar items in EconPapers)
Date: 2017
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://www.arpgweb.com/pdf-files/sr3(2)6-16.pdf (application/pdf)
http://www.arpgweb.com/?ic=journal&journal=10&month=02-2017&issue=2&volume=3 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:arp:srarsr:2017:p:6-16

Access Statistics for this article

Scientific Review is currently edited by Dr. Abdelazim Mohamed Abdelhamid Negm

More articles in Scientific Review from Academic Research Publishing Group Rahim Yar Khan 64200, Punjab, Pakistan.
Bibliographic data for series maintained by Managing Editor ().