Synthesis of Metal (II) Complexes of Co, Cu and Ni with Organic Ligand (Maleic Acid) and Their Antioxidant Activities

Wadai Smith, Hassan B. Yesufu, Emeka Walter Ndubuisi and Lawrence Ocheme Akor
Additional contact information
Wadai Smith: Department pharmaceutical chemistry, University of Maiduguri, Maiduguri
Hassan B. Yesufu: Department pharmaceutical chemistry, University of Maiduguri, Maiduguri
Emeka Walter Ndubuisi: Department pharmaceutical chemistry, University of Maiduguri, Maiduguri
Lawrence Ocheme Akor: Department pharmaceutical chemistry, University of Maiduguri, Maiduguri

International Journal of Research and Scientific Innovation, 2025, vol. 12, issue 9, 3668-3680

Abstract: Complexes of Co, Ni and Cu with maleic acid as ligand were synthesized using reported procedure and characterized using UV spectrometry. The purity of the complexes was monitored and analyzed using solubility, melting point test and the complexes were evaluated for anti-oxidant activities against 1,1-diphenyl-2-picrylhydraxyl(DPPH) free radicals. All the complexes are of good yield, they are of different colors, partially soluble in organic solvent and soluble in DMF. The result was analyzed and presented as mean± SEM. The complex of Co, Ni and Cu at the concentration of 100ug/ml, 50ug/ml, 25ug/ml and 12.5ug/ml respectively shows less scavenging activity compared to the standard (vitamin C) at all concentration. The EC50 result shows that all the complexes have less activity compared to the standard (Vit C.) but still showing notable antioxidant capacity. On the bases of the above studies, an octahedral has been proposed for the complexes.

Date: 2025
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.rsisinternational.org/journals/ijrsi/u ... -3680-202510_pdf.pdf (application/pdf)
https://www.rsisinternational.org/journals/ijrsi/article.php?id=384 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:bjc:journl:v:12:y:2025:i:9:p:3668-3680

Access Statistics for this article

International Journal of Research and Scientific Innovation is currently edited by Dr. Renu Malsaria

More articles in International Journal of Research and Scientific Innovation from International Journal of Research and Scientific Innovation (IJRSI)
Bibliographic data for series maintained by Dr. Renu Malsaria ().