Ex vivo Determination of Prostate Specific Antigen (PSA) Using Green Synthesized Magnetic Iron-Oxide Nanoparticles (IONPS)

Muhd Bk, Umar Aa, Muhammad Y., Kani Ya., Iliya S., Wali U., Tahiru A., Abubakar Uf, Shehu Z., Ahmed Ay. and Zainab I
Additional contact information
Muhd Bk: Department of Biotechnology Federal University Dutse PMB 7156, Nigeria
Umar Aa: Department of Biotechnology Federal University Dutse PMB 7156, Nigeria
Muhammad Y.: Department of Chemical pathology, Rasheed Shekoni Specialist Hospital Dutse, Nigeria
Kani Ya.: College of Medicine and Health Sciences, Federal University Dutse, Nigeria
Iliya S.: Department of Biological Sciences, School of Pure and Applied Sciences, Mount Kenya University Thika, Kenya
Wali U.: Department of Chemical Pathology Faculty of Medical Laboratory Science, Usmanu Danfodiyo University Sokoto, Nigeria
Tahiru A.: Department of Chemical pathology, Rasheed Shekoni Specialist Hospital Dutse, Nigeria
Abubakar Uf: Public Health and Diagnostic Institute, Yusuf Maitama Sule University Kano, Nigeria
Shehu Z.: Department of Chemical Pathology Faculty of Medical Laboratory Science, Usmanu Danfodiyo University Sokoto, Nigeria
Ahmed Ay.: Department of Science Laboratory Technology, Jigawa State Polytechnic, Nigeria
Zainab I: Department of Hematology and Blood Group Serology, Rasheed Shekoni Specialist Hospital Dutse, Nigeria

International Journal of Research and Scientific Innovation, 2020, vol. 7, issue 4, 296-302

Abstract: The discovery and introduction of prostate-specific antigen (PSA) testing into clinical medicine enable the diagnosis, treatment and monitoring of prostatic carcinoma, and further revolutionized the management of patients with prostate cancer. Among the current developments in molecular detection of PSA is ELISA. The current research aimed at synthesizing the magnetic Iron-oxide nanoparticles for detection (assay) of prostate specific antigen and comparing the results obtained with that of the ELISA technique. It provides new advancements in molecular detections of PSA using magnetic iron-oxide nanoparticles. The magnetites were green synthesized using blackberry leaves extract, FeCl2.4H2O and FeCl3.6H2O. Serum samples (n=30) were treated and subjected to both ELISA and magnetic iron-oxide nanoparticles immunoassay techniques. Descriptive statistical analysis (α=.05) of T-test, chi-square and ANOVA using SPSS software package, reveals (p

Date: 2020
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.rsisinternational.org/journals/ijrsi/d ... -issue-4/296-302.pdf (application/pdf)
https://www.rsisinternational.org/virtual-library/ ... nanoparticles-ionps/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:bjc:journl:v:7:y:2020:i:4:p:296-302

Access Statistics for this article

International Journal of Research and Scientific Innovation is currently edited by Dr. Renu Malsaria

More articles in International Journal of Research and Scientific Innovation from International Journal of Research and Scientific Innovation (IJRSI)
Bibliographic data for series maintained by Dr. Renu Malsaria ().