Estimation of large block structured covariance matrices: Application to ‘multi‐omic’ approaches to study seed quality
M. Perrot‐Dockès,
C. Lévy‐Leduc and
L. Rajjou
Journal of the Royal Statistical Society Series C, 2022, vol. 71, issue 1, 119-147
Abstract:
Motivated by an application in high‐throughput genomics and metabolomics, we propose a novel and fully data‐driven approach for estimating large block structured sparse covariance matrices in the case where the number of variables is much larger than the number of samples without limiting ourselves to block diagonal matrices. Our approach consists in approximating such a covariance matrix by the sum of a low‐rank sparse matrix and a diagonal matrix. Our methodology also can deal with matrices for which the block structure appears only if the columns and rows are permuted according to an unknown permutation. Our technique is implemented in the R package BlockCov which is available from the Comprehensive R Archive Network (CRAN) and from GitHub. In order to illustrate the statistical and numerical performance of our package some numerical experiments are provided as well as a thorough comparison with alternative methods. Finally, our approach is applied to the use of ‘multi‐omic’ approaches for studying seed quality.
Date: 2022
References: View references in EconPapers View complete reference list from CitEc
Citations:
Downloads: (external link)
https://doi.org/10.1111/rssc.12524
Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.
Export reference: BibTeX
RIS (EndNote, ProCite, RefMan)
HTML/Text
Persistent link: https://EconPapers.repec.org/RePEc:bla:jorssc:v:71:y:2022:i:1:p:119-147
Ordering information: This journal article can be ordered from
http://ordering.onli ... 1111/(ISSN)1467-9876
Access Statistics for this article
Journal of the Royal Statistical Society Series C is currently edited by R. Chandler and P. W. F. Smith
More articles in Journal of the Royal Statistical Society Series C from Royal Statistical Society Contact information at EDIRC.
Bibliographic data for series maintained by Wiley Content Delivery ().