Relationship between endometriosis and infertility: systematic bibliographic review

Gabriela Scarcella Santos

SAP Health and Policy, 2024

Abstract: Background: Endometriosis is a chronic condition affecting a significant percentage of women of reproductive age. It is associated with various complications, including infertility. This systematic review aims to analyze the relationship between endometriosis and infertility, addressing the underlying pathophysiological mechanisms and the impact of treatments. Material and methods: Searches were conducted in scientific databases, selecting 15 studies that met predefined criteria. Observational studies, systematic reviews, and meta-analyses were included. Data were organized to facilitate the comparison of results. Results: Findings indicate a significant association between endometriosis and infertility, with a probability of infertility ranging from 30% to 60% in diagnosed women. Hormonal, inflammatory, and oocyte quality alterations were identified as relevant pathophysiological mechanisms. Surgical treatments showed moderate benefits, though varying by case. Conclusion: Endometriosis is clearly related to infertility, emphasizing the importance of early diagnosis and appropriate management. Further research is needed to deepen the understanding of underlying mechanisms and improve treatment strategies.

Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:cwf:shpart:shp2024125

DOI: 10.56294/shp2024125

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