The Role of Epigenetics in Cancer Development: Investigating the Link between Epigenetic Modifications and Cancer

Sinigdha Islam (), Bibi Ayesa (), Dr. Mahmudul Hasan (), Md. Jobaer Rahman Rashed (), Banasree Roy Urmi (), Rajib Kumar Malakar (), Shekh Mohammad Mostafa (), Aditta Das (), Zahidul Mostafa () and Maherun Nesa ()

Journal of Artificial Intelligence General science (JAIGS) ISSN:3006-4023, 2025, vol. 8, issue 02, 01-15

Abstract: Epigenetic modifications prove critical to cancer development, so the disease stands as a major cause of death in people, according to scientific evidence. Environment and cellular alterations affect modifications that differ from genetic mutations because DNA methylation, histone modification, chromatin remodeling, and non-coding RNA activity show reversible potential. This paper thoroughly examines epigenetic methods while demonstrating how their regulatory functions help cancer development without altering DNA sequences. The research reviews how irregular DNA methylation patterns combined with modifiable histone codes and chromatin structural modifications affect tumorous heterogeneity and create drug resistance while preventing immune responses. The document evaluates epigenetic biomarker accuracy for early cancer detection and their forecasting abilities alongside modern developments in anti-epigenetic therapeutic strategies. This article integrates present multi-omics research with translational studies to develop full knowledge about how epigenetic factors define cancer biology for precise medical interventions.

Keywords: Epigenetics; Cancer Development; Epigenetic Modifications; Gene Expression; DNA Methylation; Artificial General Intelligence (AGI) (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:das:njaigs:v:8:y:2025:i:02:p:01-15:id:373

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