Case Series: Successful Visual Recovery in Central Serous Chorioretinopathy with Spironolactone Treatment

Ais Fricella (), Yasin Fadillah () and Maria Debora Niken Larasati ()

International Journal of Scientific Research and Modern Technology, 2025, vol. 4, issue 9, 154-160

Abstract: Purpose: To describe clinical outcomes of spironolactone therapy in patients with central serous chorioretinopathy (CSCR).Methods: We present a case series of three male patients diagnosed with CSCR and treated with oral spironolactone 25 mg/day for three months. All patients underwent baseline and follow-up ophthalmologic evaluation, including uncorrected visual acuity (UCVA) and optical coherence tomography (OCT).Results: All three patients showed significant anatomical and functional improvements. UCVA improved from 6/40 to 6/15 in Case 1, from 6/40 to 6/7.5 in Case 2, and from 6/40 to 6/8 in Case 3. OCT demonstrated near-complete resorption of subretinal fluid in all cases. No systemic or ocular adverse effects were reported during treatment.Conclusion: Low-dose spironolactone was effective and well tolerated in CSCR, supporting its potential as a therapeutic option in both acute and persistent cases

Keywords: Central Serous Chorioretinopathy; Spironolactone; Visual Recovery; Optical Coherence Tomography (search for similar items in EconPapers)
Date: 2025
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