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The Influence of Genetic and Environmental Factors on the Occurrence and Development of Blood Diseases

Qiaoling Wang, Qing Yuan, Jiayu Liu, Shenglin Hu, Junwu Du and Shuzhi Zhou

European Journal of Public Health and Environmental Research, 2025, vol. 1, issue 1, 80-86

Abstract: Hematopoietic disease is due to the abnormal function of the hematopoietic system, is a disease caused by the dual role of heredity and environment. Genetic factors such as gene mutation, chromosome abnormality, immune gene mutation, as well as environmental factors such as exposure to harmful chemicals, viral infection, and living habits are all risk factors for causing blood diseases. Certain gene mutations, such as TP53, JAK2, NPM1, etc., are high-risk for the occurrence of blood diseases, and long-term exposure to harmful chemicals, EBV virus infection, etc., can also lead to the occurrence of blood diseases. This article reviews the influence of genetic and environmental factors on the occurrence and development of blood diseases, and discusses the prevention and control strategies such as early screening, targeted therapy, cell therapy and personalized rehabilitation.

Keywords: blood diseases; gene mutation; environmental exposure (search for similar items in EconPapers)
Date: 2025
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