Normolipid-lowering effect of omegas in chia seed (Salvia hispanica) in wistar rats

Jimenez Granizo, Glenda Marcela, Burbano Gómez, Idrovo Encalada, Soledispa Cañarte and López Barrera

Health Leadership and Quality of Life, 2023, vol. 2, 260

Abstract: Chia seed (Salvia hispánica) constitutes a great nutritional value for considerable content of fiber, protein and polyunsaturated fatty acids, essential to keep a lipid proper health. According to studies made, it has been shown that omegas 3, 6, and 9 contained in chia contribute to improve the lipidic profile by exerting a normolipemic effect on it. The study herein evaluated the normolipemic effect of the chia seed oil, for which 6 groups of 7 rats were formed, the control group (CN) maintained a pellet base diet, of these, 5 groups were previously induced to a hypercholesterolemia with a fat rich diet for two months: one group was treated with atorvastatin (CP), 3 groups were treated with chia at concentrations of 250, 500, and 1000 mg/kg (C250, C500, C1000, respectively); a group maintained the fat rich diet (CD) until the end of the treatment. Lipid profile analysis were performed at 7, 14 and 21 days from the start of the treatment. The results showed that after 7 days the C1000 reduced its LDL and increased its HDL, showing no significant difference with the atorvastatin. At the end of day 21 the lipid profile levels improved at all doses of chia , having lower levels of cholesterol, triglycerides, LDL and HDL levels being higher, even above the CN, showing significant difference with the CD, with a statistical probability of (p

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:dbk:health:v:2:y:2023:i::p:260:id:260

DOI: 10.56294/hl2023260

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