Endothelial dysfunction in patients exposed to cardiovascular risk factors

Carbonell Amiot, Montes de Oca Carmenaty, Bringues Segura and Romero García

Health Leadership and Quality of Life, 2024, vol. 3, .456

Abstract: Introduction: Cardiovascular diseases are the leading cause of death globally. 90% of them derive from cardiovascular risk factors, the modification of which makes it possible to reverse their harmful consequences. Objective: Identify the presence of endothelial dysfunction in patients exposed to classic cardiovascular risk factors. Method: An observational, descriptive study of case series was carried out with a sample n=106 of patients exposed to classic cardiovascular risk factors, during the period January 2022 to January 2024, treated in a specialized cardiological prevention clinic, at the Cardiology Center. and Cardiovascular Surgery, “Saturnino Lora” Provincial Hospital, Santiago de Cuba. Results: The most altered endothelial function was vasomotor, the highest proportion was found in the group of sick patients, reaching 88.68%. The second most altered function of the vascular endothelium was the inflammatory response, which generally reached proportions of 79.24 and 76.42%. The increase in the intima-media thickness of the carotid artery above 0.8 mm has a strong association with the appearance of CVD (p=0.000; V=0.531), followed by the us CRP value (p=0.001 ; V=0.333). Conclusions: It is concluded that there is an association between the presence of a dysfunctional vascular endothelium and the appearance of cardiovascular disease, determined predominantly by an alteration of vasomotor function and the inflammatory response.

Date: 2024
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Persistent link: https://EconPapers.repec.org/RePEc:dbk:health:v:3:y:2024:i::p:.456:id:.456

DOI: 10.56294/hl2024.456

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