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Risk factors for infectious endocarditis of prosthetic valves: a systematic review

Sara Isabel Vasquez Torrico and Gerardo Laube

SCT Proceedings in Interdisciplinary Insights and Innovations, 2024, vol. 2, 10.56294/piii2024333

Abstract: Introduction: valve endocarditis is a major health challenge; its etiology is varied, and it can cause multiple complications or death. to identify risk factors for infective endocarditis in prosthetic valves. systematic and retrospective review of the available literature using records from Pubmed, Epistemonikos, Cochrane library, Uptodate. in Argentina, from September 2013 to March 2016, 502 patients with infective endocarditis (IE) were studied in 48 medical centers. The majority were men (69,9 %) with a mean age of 60,7 years. The main risk factors were known underlying heart disease (45,36 %), diabetes (23,5 %), chronic renal failure (16,5 %), neoplastic disease (12,1 %) and history of previous IE (8,96 %). The most frequent predisposing events were endovascular (31,9 %) and dental (12,6 %) procedures. New causes of IE related to gastrointestinal pathologies were also identified. patients with IE have a high clinical risk profile and show increasing age over the decades. Staphylococcus aureus is the most frequent microorganism followed by Streptococcus viridans. The identification of independent predictors of in-hospital mortality continues to be a challenge due to the new agents that are identified or risk factors that are added over time; identifying them could help to establish behavioral modification strategies that lead to improved outcomes

Date: 2024
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