Factors Associated, Symptoms, and Treatments of Guillain-Barré Syndrome: A Narrative Review

Emilia López-Peña, Diana Camizán-Julca, Jonathan Dávila-Pezo, Sayra Morales-Ruiz, Víctor Álvarez-Manrique, Mardel Morales-García, Liset Z. Sairitupa-Sanchez and Wilter C. Wilter C. Morales-García

Salud Integral y Comunitaria, 2025, vol. 3, 183-183

Abstract: Objective: To conduct a brief literature review on Guillain-Barré Syndrome (GBS), its associated factors, and available treatments. Design: Literature review based on a narrative synthesis. Databases: Scopus, ScienceDirect, SciELO, Google Scholar, and PubMed. Study Selection: Documents were selected through a critical literature review, considering inclusion and exclusion criteria. Results: The literature analysis included a corpus of 15 articles, comprising 2 statistical analyses, 6 narrative reviews, 3 systematic reviews, 2 observational studies, and 2 clinical cases. The studies primarily involved a population of adult men and women, children, and pregnant women, mostly from low-income and vulnerable backgrounds. Patients diagnosed with GBS were associated with COVID-19, Systemic Lupus Erythematosus (SLE), Posterior Reversible Encephalopathy Syndrome (PRES), Zika virus, and dengue. Conclusions: Research related to GBS highlights numerous causes and complications. GBS is significantly associated with muscle weakness, reduced mobility, and conditions such as SLE and PRES. During the COVID-19 pandemic, a slight increase in GBS cases was recorded. Although uncommon, GBS complications can lead to cardiovascular, respiratory, and gastrointestinal issues. Research does not explore in-depth preventive strategies or early management of these complications. There are currently limited treatments available to improve patient outcomes.

Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:dbk:sicomu:2025v3a32

DOI: 10.62486/sic2025183

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