Modeling cost-effectiveness analysis of treatment sequencing

Cristina del Campo, Jiaru Bai and L. Robin Keller

Socio-Economic Planning Sciences, 2025, vol. 99, issue C

Abstract: In clinical practice, patients with cancer often undergo treatment with a sequence of drugs, usually because of diminishing effectiveness over time or resistance development. However, few cost-effectiveness analyses have included that fact in their model. This paper aims at closing that gap by presenting a model that reflects the possibility of the patient switching from one therapeutic agent to another one throughout the long-term duration of his/her life.

Keywords: Decision analysis; Treatment sequencing; Multiple lines of treatment; Markov model; Cost-effectiveness analysis (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:eee:soceps:v:99:y:2025:i:c:s003801212500059x

DOI: 10.1016/j.seps.2025.102210

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