The Gut Microbiota in Epilepsy: Current Concepts of Mechanisms and Potential Therapeutics

Rikky Dwiyanto Sulistyo
Additional contact information
Rikky Dwiyanto Sulistyo: Dr. Cipto Panti Wilasa Hospital, Indonesia

European Journal of Biology and Biotechnology, 2022, vol. 3, issue 1, 5-9

Abstract: Epilepsy is a non-communicable brain disorder characterized by an individual's proclivity for spontaneous epileptic seizures. Epilepsy may be classified into six types: genetic, structural, metabolic, infectious, immune-related, and unexplained causes. Numerous current findings have shown evidence that an imbalance in the gut microbiota is a cause of epilepsy. Between the gut microbiota and the brain systems, there are five putative communication pathways. The neuroendocrine hypothalamic-pituitary-adrenal (HPA) axis, intestinal bacteria's production of neurotransmitters, the intestinal immune system, and the relationship between the intestinal mucosal barrier and the blood-brain barrier are among them. Future epilepsy interventions might include modifications of antiepileptic medications, a ketogenic diet, and probiotics as a possible treatment in the gut flora. However, further research is required to assess long-term therapeutic benefits.

Keywords: Epilepsy; gut microbiota; nketogenic diet; eurological disease; probiotics (search for similar items in EconPapers)
Date: 2022
References: Add references at CitEc
Citations:

Downloads: (external link)
https://eu-opensci.org/index.php/ejbio/article/view/17331 Abstract page (text/html)
https://eu-opensci.org/index.php/ejbio/article/download/17331/4224 Full text (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:epw:ejbio0:v:3:y:2022:i:1:id:17331

DOI: 10.24018/ejbio.2022.3.1.331

Access Statistics for this article

More articles in European Journal of Biology and Biotechnology from European Open Science
Bibliographic data for series maintained by Support Team ().