Kaposi's Sarcoma and Lymphoedema in a HIV Sero-positive Patient: A Case Report and Literature Review

M. S. Turton, I. Reddy and L. P. Turton
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M. S. Turton: Wits University, South Africa
I. Reddy: JDJ Laboratory, South Africa
L. P. Turton: Turton Dental Surgery and Laboratory, South Africa

European Journal of Dental and Oral Health, 2021, vol. 2, issue 5, 12-17

Abstract: Kaposi sarcoma (KS) is one of the most common neoplasms diagnosed in HIV- seropositive subjects. KS is an angioproliferative disorder of endothelial origin and is a locally aggressive multicentric mucocutaneous malignant neoplasm. Aggressive HIV-KS is associated with increased HHV8 viral load, disseminated lesions, and intraoral exophytic lesions, and may also present with facial lymphoedema which may be life-threatening or mild. A 26 -year-old, male, presented with severe oral pain and facial swelling. He had multiple oral lesions and an incisional biopsy confirmed Kaposi sarcoma. A multiple site incisional biopsy and immunohistochemistry for HHV8 was done and based on the clinical, histopathological, and immunohistochemical results a diagnosis of HIV associated oral and cutaneous KS with severe lymphoedema was confirmed. This aim of this case presentation is to describe a case of immunodeficiency virus-related lymphadenitis, oral and cutaneous KS associated with the complication severe lymphoedema in a HIV infected patient who was not on HAART therapy for three years after being diagnosed with HIV.

Keywords: HIV; Kaposi's sarcoma; lymphoedema; human herpes virus (search for similar items in EconPapers)
Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:epw:ejdent:v:2:y:2021:i:5:id:13096

DOI: 10.24018/ejdent.2021.2.5.96

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