Root Anomalies after Combined Chemotherapy Treatment for Acute Lymphoblastic Leukemia during Childhood: A Case Report‬‬‬‬‬‬‬‬‬‬‬‬‬

Talia Becker, Ella Lalum, Avi Levin, Joe Ben Itzhak, Idan Stiklaru and Michael Solomonov
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Talia Becker: Hebrew University of Jerusalem, Israel
Ella Lalum: Israel Defense Forces Medical Corps, Israel
Avi Levin: Israel Defense Forces Medical Corps, Israel
Joe Ben Itzhak: Israel Defense Forces Medical Corps, Israel
Idan Stiklaru: Israel Defense Forces Medical Corps, Israel
Michael Solomonov: Israel Defense Forces Medical Corps, Israel

European Journal of Dental and Oral Health, 2023, vol. 4, issue 2, 18-22

Abstract: Dental abnormalities have been sporadically reported in patients treated as children for acute lymphoblastic leukemia (ALL) with multi-agent chemotherapy, with and without radiation. Reports included delayed dental development, microdontia, hypoplasia, agenesis, V-shaped roots, shortened roots, and cervical root resorption. These anomalies in pediatric patients require regular dental follow-up and sometimes highly complex treatment. We describe a well-documented case of a 19-year-old male who presented with such anomalies 12 years after treatment with several chemotherapy agents for ALL, and discuss the resultant disruption of normal tooth development that led to the ensuing abnormalities.

Keywords: Acute lymphoblastic leukemia; dental abnormalities; multi-agent chemotherapy; shortened roots; tooth development (search for similar items in EconPapers)
Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:epw:ejdent:v:4:y:2023:i:2:id:13260

DOI: 10.24018/ejdent.2023.4.2.260

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