Flexible Insulin Therapy: Results of a Tunisian Experience

Hajer Kandara, Chaima Jemai, Abdennebi Cyrine, Jemel Manel and Kammoun Ines
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Hajer Kandara: National institute of nutrition of Tunis, Tunisia
Chaima Jemai: National institute of nutrition of Tunis, Tunisia
Abdennebi Cyrine: National institute of nutrition of Tunis, Tunisia
Jemel Manel: National institute of nutrition of Tunis, Tunisia
Kammoun Ines: National institute of nutrition of Tunis, Tunisia

European Journal of Medical and Health Sciences, 2020, vol. 2, issue 4

Abstract: Aims: To evaluate the adherence of type 1 diabetic patients to long-term flexible insulin therapy (FIT), and the impact of this approach on the glycemic balance, basal insuline dose and quality of life of patients. Methods: This is a rospective descriptive study, conducted between January and April 2017, including 50 patients with type 1 diabetes having following the FIT of department B of Endocrinology-Diabetology and Metabolic Diseases service B at the National Institute of Nutrition and Food Technology of Tunis. Results: The FIT decreased mean HbA1c from 8.96% to 7.57% (p=0.04) and mean basal insulin dose from 0.35 to 0.27 IU/kg /day. Hypoglycemia's frequency decreased from 3.2±2.1 to 0.93±2.1 episodes /patient /week (p=0.03), with improved quality of life. However, there was a significant weight gain (p=0.02). Conclusions: FIT allows for better glycemic control while reducing hypoglycemia, especially severe episodes, and improves the quality of life of patients with type 1 diabetes but seems to cause weight gain.

Keywords: Flexible Insulin therapy; Type 1 Diabetes; Therapeutic education; Blood glucose. (search for similar items in EconPapers)
Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:epw:ejmed0:v:2:y:2020:i:4:id:40243

DOI: 10.24018/ejmed.2020.2.4.243

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