Epidemiological Clinical and Profile of Cranio-spinal Dysraphisms in Madagascar

Bemora Joseph Synèse, Andrianaivo Radotina Tony, Masina Ndalana d’Assise, Ratovondrainy Willy, Rabararijaona Mamiarisoa and Andriamamonjy Clément
Additional contact information
Bemora Joseph Synèse: CHU-JRA, Madagascar
Andrianaivo Radotina Tony: CHU-JRA, Madagascar
Masina Ndalana d’Assise: CHU-JRA, Madagascar
Ratovondrainy Willy: CENHOSOA, Madagascar
Rabararijaona Mamiarisoa: CHU Tambohobe Fianarantsoa, Madagascar
Andriamamonjy Clément: CHU-JRA, Madagascar

European Journal of Medical and Health Sciences, 2020, vol. 2, issue 6

Abstract: Cranio-spinal dysraphisms are a set of congenital malformations resulting from a defect in closing the neural tube during embryonic development. The objective of this study was to describe the epidemiological-clinical profile of these malformations in Madagascar. It was a retrospective, descriptive study and metacentric from January 01, 2016 to December 31, 2018; all cases of cranio-spinal dysraphisms seen in two neurosurgery centers in Madagascar. We have collected 32 cases of cranio-spinal dysraphisms. The hospital prevalence was 0.37%. Among these children, the mean age was 8.48 months with an extreme of 1 day to 6 years; there was a feminine predominance (53,12%), with a sex ratio of 0.88. The absence of maternal intake of folic acid, the intake of folic acid outside the recommended periods, the birth order of the children and maternal pathologies during pregnancy were found as etiology. Cranial topography predominated in 56.25% (18 cases) and 68.75% of the children were asymptomatic. An association with hydrocephalus was found in 31.25% of cases. Prevention of known risk factors is essential, antenatal diagnosis is important for early management and improved prognosis. The treatment is surgical.

Keywords: Etiology; surgery; Neural Tube Defects; Hydrocephalus (search for similar items in EconPapers)
Date: 2020
References: Add references at CitEc
Citations:

Downloads: (external link)
https://eu-opensci.org/index.php/ejmed/article/view/40606 Abstract page (text/html)
https://eu-opensci.org/index.php/ejmed/article/download/40606/9062 Full text (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:epw:ejmed0:v:2:y:2020:i:6:id:40606

DOI: 10.24018/ejmed.2020.2.6.606

Access Statistics for this article

More articles in European Journal of Medical and Health Sciences from European Open Science
Bibliographic data for series maintained by Support ().