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Efficacy of Ashwagandha Extract Formulation (ASVAMAN®) on Improvement of Energy and Endurance: A Randomized, Double-blind, Placebo-controlled Clinical Study in Healthy Adults

Naveen Puttaswamy, Gaurav Singh, Anand Mayachari, Madhukumar Parameswaran and Venkateshwarlu Kudiganti

European Journal of Medical and Health Sciences, 2025, vol. 7, issue 2, 88-93

Abstract: Background: Ashwagandha (Withania somnifera) is a traditional herb that holds a significant place in Ayurvedic medicine, recognized as both a “rasayana” and “adaptogen”. Objective: This study aimed to evaluate the effects of Ashwagandha root extract (ASVAMAN®) on the energy and endurance in healthy adults. Methods: In this randomized, double-blind, placebo-controlled study, 40 healthy male participants with a body mass index (BMI) ranging from 20.0 to 25.9 kg/m2 were randomly allocated to receive either 300 mg of ASVAMAN® twice daily (n = 20) or a placebo (n = 20) for a duration of 42 days. The primary efficacy outcomes were evaluated using 6-minute walk test (6 MWT) scores and serum cortisol levels, measured from baseline to the conclusion of the study (42 days). Secondary outcomes were assessed using the stair climbing test (SCT), chair standing test (CST), 30-meter walk test (30 MWT), one-leg stance (OLS) test, serum testosterone levels, and 36-item short-form survey (SF-36) quality of life scores. Results: Compared to the placebo group, Asvaman® supplementation led to a significant improvement (p

Keywords: ASVAMAN®; cortisol; endurance; energy (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:epw:ejmed0:v:7:y:2025:i:2:id:42304

DOI: 10.24018/ejmed.2025.7.2.2304

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