Role of Secondary Metabolites in Alpha-Amylase Inhibition in Diabetes

Spriha, Puneet, Gurinder Singh and Harpreet Kaur

International Journal of Scientific Research in Science and Technology, 2025, vol. 12, issue 4, 1080-1090

Abstract: This study aims to establish the anti-diabetic potential of three medicinal plant yucca, Buxus bonsai , and Syngonium, this study adopted phytochemical screening tests. Widely allowed methods to assess antioxidant strength (DPPH assay), phenolic level (Folin-Ciocalteu method), and antibacterial activity (disc diffusion) were observed to test ethanol fresh leaves extract. The results indicated the differences in the phytochemical compositions of the plants. Yucca was the highest in phenolics (1.7 mg/mL) and the most potent in antioxidant activity (67.8% DPPH scavenging) and Buxus bonsai had the highest anti-diabetic profile with 66.16 percent inhibition of α-amylase. Syngonium failed to exhibit any significant symptom of alpha-amylase inhibition but demonstrated high levels of antibacterial activity. These findings indicate that Yucca possess significant antioxidant properties and Buxus bonsai possesses high anti-diabetic potential. The evidence further requests additional clinical studies and sustains the healing capabilities of these medicinal plants as a treatment of diabetes.

Keywords: Diabetes mellitus; α-amylase inhibition; medicinal plants; Yucca; Buxus bonsai; Syngonium; antioxidant activity; phenolic estimation; DPPH assay (search for similar items in EconPapers)
Date: 2025
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Persistent link: https://EconPapers.repec.org/RePEc:etm:ijsrst:v12:y2025:i4:id:1114

DOI: 10.32628/IJSRST251393

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